Deadpool

Ryan Reynolds

Wade / Deadpool

Karan Soni

Dopinder

Ed Skrein

Ajax

Michael Benyaer

Warlord

Stefan Kapičić

Colossus (voix)

Brianna Hildebrand

Negasonic Teenage Warhead

Style Dayne

Jeremy (Pizza Guy)

Kyle Cassie

Gavin Merchant

Taylor Hickson

Meghan Orlovsky

Naika Toussaint

Teen Girl #2

Randal Reeder

Buck

T. J. Miller

Weasel

Isaac C. Singleton Jr.

Boothe

Morena Baccarin

Vanessa

Donna Yamamoto

Oncologist

Jed Rees

Recruiter

Hugh Scott

David Cunningham

Gina Carano

Angel Dust

Cindy Piper

Chinatown Merchant

Chad Riley

Pool Hall Goon

Darcey Johnson

Garbage Truck Driver

Leslie Uggams

Blind Al

Kyle Rideout

Super Soldier #1

Jason William Day

Super Soldier #2

Stan Lee

Strip Club DJ

Ben Wilkinson

No5 Orange Manager

Paul Lazenby

Flight Deck Guard

Rob Hayter

Bob