Machete Kills

Danny Trejo

Machete Cortez

Mel Gibson

Luther Voz

Demián Bichir

Mendez

Amber Heard

Blanca Vasquez / Miss San Antonio

Michelle Rodriguez

Luz

Sofía Vergara

Desdemona

Charlie Sheen

Mr. President

Jessica Alba

Sartana Rivera

Tom Savini

Osiris Amanpour

Vanessa Hudgens

Cereza Desdemona

Lady Gaga

La Camaleon

Cuba Gooding Jr.

El Camaleon

Antonio Banderas

El Camaleon

Walton Goggins

El Camaleon

William Sadler

Sheriff Doakes

Alexa PenaVega

KillJoy

Marko Zaror

Zaror

Julio Oscar Mechoso

Chepo

Billy Blair

Billy

Samuel Davis

Clebourne

Felix Sabates

Doc Felix

Electra Avellan

Nurse Mona

Elise Avellan

Nurse Lisa

Marci Madison

Nurse Fine

Callie Hernandez

Space Babe

Alejandro Antonio

Boss of Mendez

Crystal Martinez

Wife of Mendez

Corey Burton

Trailer Voice Guy (voix)

Elon Musk

Elon Musk

Emmy Robbin

Pris

Jason Christopher

Lieutenant Brass

J.J. Perry

Voz's Henchman (non-crédité)